WebF Scheffauer is an academic researcher. The author has contributed to research in topic(s): Patch clamp & Heparin. The author has an hindex of 1, co-authored 1 publication(s) receiving 56 citation(s). WebPetra Eder, Rainer Schindl, Christoph Romanin, and Klaus Groschner. Author Information and Affiliations Authors Petra Eder,1Rainer Schindl,2Christoph Romanin,2and Klaus Groschner1. Affiliations 1Karl …

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WebChristoph Romanin; Activation of immune cells is triggered by the Ca2+ release-activated Ca2+ current, which is mediated via channels of the Orai protein family. A key gating process of the three ... WebSep 10, 2009 · Christoph Romanin Institute of Biophysics University of Linz A-4040 Linz Austria Tel.: +43 732 2468 9272 Fax: +43 732 2468 9280 e-mail: … ion ct chest

F Scheffauer 1 Publications 56 Citations Related Authors

WebJul 17, 2024 · The initial activation step in gating of ubiquitously expressed Orai1 Calcium (Ca2+) ion channels represents the store-dependent coupling to the Ca2+ sensor protein STIM1. An array of constitutively active Orai1 mutants gave rise to the hypothesis that STIM1 mediated Orai1 pore opening is accompanied by a global conformational change … WebOct 4, 2013 · Introduction. The CRAC 4 channel signaling machinery consists of two key components, STIM1 (1, 2) and Orai (3–5).STIM1 acts as an endoplasmic reticulum-located Ca 2+ sensor and mediates CRAC channel activation (1, 2, 6).After endoplasmic reticulum Ca 2+ store depletion, STIM1 multimerizes and redistributes into punctae close to the … WebHis Voltage-dependent calcium channel research includes themes of Store-operated calcium entry and Pharmacology. His biological study spans a wide range of topics, including Cancer research, CD8, Immune system and Cytotoxicity. He most often published in these fields: Cell biology (45.86%) Biophysics (21.02%) Cytotoxic T cell (19.11%) ontario immigration act